Reliability of Self-Reported Medical Histories in Older Adults With and Without
  
   Lead Investigator:    Nicholas Curcio
   Institution      :    UT-Southwestern Medical Center
   E-Mail           :    Nicholas.Curcio@UTSouthwestern.edu
   Proposal ID      :    915


   Publications:


1  Curcio N, Wilmoth K, LoBue C, Cullum M
   Reliability of Medical History Reporting in Older Adults With and Without Cognitive Impairment
   Journal Article  J Cent Nerv Syst Dis,11:1-9,2019,PMC6477758

   PUBLISHED





   Proposal Description:
   My research aims are as follows: I plan on assessing self-report reliability of   self-reported medical event histories, including both remote neurological and     remote cardiac events by utilizing Cohen?s Kappa and computing percentage         agreement across two time points (Initial and first follow up ADC visits).        Subjects will be included in analyses if they are aged 50 years or older,         completed an initial and follow-up visit within 6 to 12 months, and  are          classified as having normal cognition, MCI, or possible or probable AD at both    time points. Variables of interest will include 5 neurological events (Stroke,    TIA, Seizure, TBI <5min LOC, and TBI >5min LOC) and 6 cardiac events (Heart       attack/cardiac arrest, Atrial fibrillation, angioplasty, Cardiac Bypass,          pacemaker implantation, and congestive heart failure). Diagnostic groups          (Normal cognition, MCI, and AD) will be compared to assess if any differences     in reporting exist between diagnostic groups. Additionally, I would like to       compare self-reported histories to clinician verified medical conditions (i.e.    myocardial infarction, atrial fibrillation, CHF) found on Form D2 in the UDS.     Sociodemographic information will also be assessed to describe differences        between diagnostic groups using chi square analyses.